Effects of Parkinsons Disease

World Parkinson’s day was described by English Physician Dr. J. Parkinson, celebrated on 11th of April every year for public awareness about Parkinson’s disease. Parkinson’s is caused by group of neurological disorder, developed gradually, also produce abnormalities of striatum (basal ganglia) function. It has its effect on cognitive function. Parkinson is chronic progressive disease of nervous system, where neurotransmitter (dopamine) delivery to other cells are reduced. It is a complex condition that changes with time. It shows both motor and non-motor symptoms. Symptoms The complex disease include motor impairments, caused due to decrease in dopa-mine level.The motor symptoms of Parkinson’s are based around involuntary movements or rigidity (in which muscles of the body ‘freeze up’ and do not work). Symptoms cannot be predicted and vary on a time scale as short as one minute.
  • Bradykinesia (slow movement)
  • Tremor
  • Postural inability
  • Gait difficulty
  • REM sleep behavioral disorder
  • Reduced sense of smell
  • Automatic dysfunction
  • Depression
  • Impaired Vision
  • Attention Deficit
  • Planning and performing ordinary tasks becomes difficult
 What happens in Parkinson’s disease
  • Dopaminergic neuron degeneration
  • Neurons containing melanin are lost which produce characteristic changes in depigmentation
  • Formation of LEWY bodies
  • Loss of dopa-mine
  • Stages of Parkinson’s Disease:



Stage I

(Mild to moderate)

  • One side of body is affected

  • Minimal or no functional impairment

Stage II

  • Both side of body are affected

  • Posture and balance are normal

Stage III


  • Affects both side of the body

  • Mild imbalance in posture and balance(walking or standing)

  • Person remain independent

Stage IV


  • Affects both side of the body

  • Severe imbalance in posture and balance (disabling ability in walking or standing)

  • Preson needs substantial help and can not live alone

Stage V


  • Fully developed disease

  • Person restricted on bed or wheelchair

Drug Therapy Drug therapy does not prevent or slow disease progression. It improves quality of life, Drug therapy which stimulate the dopaminergic system and control the excitation in cholinergic pathways. Our Related Products
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