Effects of Parkinsons Disease
World Parkinson’s day was described by English Physician Dr. J. Parkinson, celebrated on 11th of April every year for public awareness about Parkinson’s disease. Parkinson’s is caused by group of neurological disorder, developed gradually, also produce abnormalities of striatum (basal ganglia) function. It has its effect on cognitive function. Parkinson is chronic progressive disease of nervous system, where neurotransmitter (dopamine) delivery to other cells are reduced. It is a complex condition that changes with time. It shows both motor and non-motor symptoms. Symptoms The complex disease include motor impairments, caused due to decrease in dopa-mine level.The motor symptoms of Parkinson’s are based around involuntary movements or rigidity (in which muscles of the body ‘freeze up’ and do not work). Symptoms cannot be predicted and vary on a time scale as short as one minute.- Bradykinesia (slow movement)
- Tremor
- Postural inability
- Gait difficulty
- REM sleep behavioral disorder
- Reduced sense of smell
- Automatic dysfunction
- Depression
- Impaired Vision
- Attention Deficit
- Planning and performing ordinary tasks becomes difficult
- Dopaminergic neuron degeneration
- Neurons containing melanin are lost which produce characteristic changes in depigmentation
- Formation of LEWY bodies
- Loss of dopa-mine
- Stages of Parkinson’s Disease:
STAGES |
SYMPTOMS |
Stage I (Mild to moderate) |
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Stage II |
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Stage III (Moderate) |
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Stage IV (Advanced) |
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Stage V (Severe) |
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